产品货号：
Z15633
中文名称：
EPHA3抗体
英文名称：
Anti-EPHA3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EPHA3 Antibody |
| 指标别名 | EPHA3;ETK;ETK1;HEK;TYRO4;EK4;hEK4;HEK;Human embryo kinase;Eph-like tyrosine kinase 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | EPHA3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Eph receptor A3/EPHA3 recombinant protein (Position:D59-A514). |
| 实际分子量 | 135KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Ephrin Receptor EphA3,is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1).Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases;PTKs),such as EPHA3,form a structurally related group of molecules that exhibit functional diversity.Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic.Many growth factor receptors are PTKs,e.g.,the receptors for epidermal growth factor(EGFR),platelet-derived growth factor(PDGFR1;PDGFR2),colony-stimulating factor-1(CSF1R),and stem cell growth factor.The EPHA3 gene is mapped to 3p11.2.Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases.Within axial nerves,establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections. |
| Uniprot ID | P29320 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | EPH receptor A3 |
| 蛋白名全称 | Ephrin type-A receptor 3 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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